Maryland Shared Open Access Repository

MD-SOAR is a shared digital repository platform for twelve colleges and universities in Maryland. It is currently funded by the University System of Maryland and Affiliated Institutions (USMAI) Library Consortium (usmai.org) and other participating partner institutions. MD-SOAR is jointly governed by all participating libraries, who have agreed to share policies and practices that are necessary and appropriate for the shared platform. Within this broad framework, each library provides customized repository services and collections that meet local institutional needs. Please follow the links below to learn more about each library's repository services and collections.

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Recent Submissions

An In Vitro Study of the Uptake and Release of Ribavirin and It's Effect on the Osmotic Fragility of Rat, Rhesus Monkey and Human Erythrocytes
(1981-09) Spears, Charles T.; Hood College Biology; Biomedical and Environmental Science
Recent studies indicate that ribavirin, a synthetic antiviral agent, may have an unusual affinity for rhesus monkey erythrocytes not detected in rat erythrocytes (14). Experiments were designed to estimate the uptake and release of ribavirin at 4°C and 37°C, via ¹⁴C-ribavirin, and to determine the drug's effect on osmotic fragility of rat, rhesus monkey and human erythrocytes. The results of the uptake studies show that monkey RBC's have a much stronger affinity for ribavirin than either rat or human RBC's and that uptake of ribavirin at 37°C is an energy requiring process. The release of ribavirin is an apparent equilibrium reaction that proceeds, via facilitated diffusion, in the direction of the concentration gradient: Free Rib⇆ Rib-P ⇆ Rib-P-P ⇆ Rib-P-P-P The osmotic fragility curves of fresh RBC's from the respective species, incubated 2.5 hours with ribavirin, showed no significant change from the control curves. However, monkey RBC's incubated 2.5 hours with 4095 μM ribavirin and an additional 21.5 hours in drug-free media became significantly more resistant to osmotic lysis. Rat and human RBC's similarly treated were not detectably affected. These data indicate that the uptake and release mechanisms for ribavirin are similar for all three species and that the effect of ribavirin on the osmotic fragility of fresh RBC's is not detectable.
THE CANDOMBLE RELIGION: A SOURCE OF ECONOMIC AND SOCIAL EMPOWERMENT FOR AFRO-BRAZILIAN WOMEN
(2008-01) Spaulding, Rachel Elizabeth; Hood College Arts and Humanities; Humanities
In my paper I focus on the role that the religion of Candomble plays in the development of the female identity in the Afro-Brazilian culture. It explores the conflation of the belief structures of the indigenous peoples, the spiritual ideologies of the African-Yoruba cultures and the Catholic faith. Moreover, as an extension of defining woman and defining what is sacred, it considers the symbolic nature of blood sacrifice as a confirmation of a deified status. It examines the space and the boundaries that these women inhabit when attempting to construct a true meaning and understanding of what it is to be a woman living in an Afro-Brazilian culture. Also, it takes into consideration the role religion plays in revealing the status of women who exist in this space, and as a consequence, the way the religion itself then becomes an influencing factor upon the definition of women in this culture. I develop a discussion about what is worshipped and held sacred with regards to the status of women as an underlying ideal which has a direct relationship to the political and economic realities for women in this Afro-Brazilian setting. As such, it considers various religious, social, economic and political theories that contribute in outlining the role of the Afro-Brazilian woman. It is my contention that women in the Afro-Brazilian culture have greater access to the resources of their societies based on an elevated quasi-deified status derivative of their role as priestesses of Candomble houses.
Characterization of Equine Infectious Anemia Virus gag Gene-encoded Proteins and the Complete Amino Acid Sequence of the Nucleic Acid Binding Protein.
(1986-07) Sowder, Raymond C. II; Hood College Biology; Biomedical and Environmental Science
The gag proteins of equine infectious anemia virus (EIAV) were purified by reverse phase high pressure chromatography. The complete amino acid sequence of the nucleic acid binding protein (p11), as well as partial amino- and carboxy- terminal sequences of the other gag proteins (p15, p26, p9) was determined by chemical analysis on the purified proteins. The amino-terminal gag protein was blocked to Edman degradation. Immune Autoradiography allowed deduction of the gag gene order (p15-p26-pll-p9). These data provided partial confirmation of the nucleotide sequence of Stephens, et al. (132). The complete amino acid sequence of EIAV pll was determined and contained two sets of cysteine arrays. The cysteine array represents one of the most invariant amino acid sequences known to exist in retroviruses. Arrays contain conserved residues which include cysteines at positions n, n+3, n+13. It was postulated that the presence of an aromatic residue at positions n+1 or n+2 may be necessary for an array to be fully functional in binding viral RNA. The presence of a double set of "complete" cysteine arrays is correlated with the presence of the unusual rod shaped core characteristic of lentiviruses. A causal relationship is suggested. Analysis by fluorescent enhancement indicated a biphasic binding of EIAV pll to poly(etheno adenylic acid). The first stage of binding was non-cooperative, while the second stage involved cooperativity. It was concluded that EIAV pll might serve as a good model for studying the interactions of lentiviral nucleic acid binding proteins with RNA.
LA IMPORTANCIA DE LA SUBJETIVIDAD DEL TESTIMONIO EN LA POST-DICTADURA ARGENTINA
(2009-08) Sor, Emiliano; Hood College Arts and Humanities; Humanities
Back When We Were Normal: Marriage, Death, and the Death of a Marriage
(2025-12-04) Saint-James, Molly; Billings Noble, Randon; Orange, Michelle; MFA in Creative Nonfiction
In Back When We Were Normal, Molly grapples with how to grieve: how to grieve a struggling marriage interrupted by her young husband's death, how to talk about grief that doesn’t match anybody's—least of all, her—expectations, and how to come to terms with both the pain and surprising joy of starting a new life.